Custom synthesis at AlzChem - many years of experience and diverse technologies

Toll manufacturing

In our multi-purpose plants at the Trostberg site, a multitude of technologies for custom syntheses are at your disposal. Besides cyanamide and heterocycle chemistry, our expertise includes Grignard syntheses and gas phase reactions. As part of our custom manufacturing activities, we operate equipment for the safe handling of highly air- and moisture-sensitive organometallic products. In addition to Grignard reactions, the current portfolio includes the handling of silicon, lithium, aluminum and titanium compounds.

Flexibility and speed with high implementation rates for new projects are important competencies of AlzChem. By establishing a cross-functional organization we have exactly the right people in a team to work on projects efficiently and implement decisions quickly. Successful growth with our customers confirms our modern way of teamwork.

Dr. Alexander Dippold

Dr. Alexander Dippold

There are various ways of co-operation.

AlzChem’s Development Process is highly flexible in order to facilitate an entry into each project phase:

You have an idea, but not the research capability to realize it? We would be happy to co-operate with you on the research. We will take all the time required to discuss your idea with you; we will listen to you and try to understand your requirements, so that an optimal commercial process may be achieved. Trust in one another is for us the basis for successful co-operation.

You may have a simple laboratory synthesis? Upscaling is necessary in order to establish a commercial process and you do not have this capability? Our process optimization methods will analyze your synthesis and identify potential areas of improvement!

Alternatively, you already have a technically sound synthesis procedure, but not the necessary production capacity? With our long-standing experience, we can quickly give you a price indication for a production on any scale. A large range of technologies and modern facilities enable us to carry out a multitude of reaction types as well as multi-step syntheses.

It is our goal to provide product of highest quality combined with an exceptional level of service considering customer specific needs. Needless to add that confidentiality is an integral part of each custom specific Project.

Each phase is accompanied by our in-house support functions:

AlzChem has long-standing experience in many fields of organic synthetic chemistry. Numerous procedures are implemented using a broad range of reaction technologies, raw materials and production Equipment:

Core Technologies:

  • Large scale Grignard reactions
  • Gas phase reactions (ammoxidation/ ammonolysis)
  • Synthesis of N-C-N Heterocycles (pyrimidines, triazines, triazoles)
  • Guanylation
  • Dehydrogenation
  • Moisture and oxygen-free conditions
  • Air sensitive / organometallic reactions
  • Multi-step synthesis

Challenging Chemicals:

  • Diethyl Ether
  • Cyanamide
  • Acid chlorides
  • Isocyanates
  • Highly "active" compounds

We can commercialize your synthesis quickly and reliably. We are also pleased to determine any safety-relevant technical data for you and we will also deal with any necessary registrations on your behalf.
Pharmaceutical products and their precursors can be produced according to GMP conditions.

UTILITIES

  Multipurpose Plants GMP
    large medium small Plant
STEAM 6 bars / 160° X X X X
BRINE -20 °C X X X X
  -50 °C X - X -
HEAT TRANSFER OIL up to 200-250 °C X X X -

 

MATERIALS   Multipurpose Plants GMP
    large medium small Plant
STEEL GRADES 1.4571 x x x x
  1.4539 x x x x
  Hastelloy - - x x
GLASS-LINED STEEL   x x x x
GRAPHITE HEAT EXCHANGER   x x x -

 

REACTORS   Multipurpose Plants GMP
    large medium small Plant
NUMBER   8 6 9 4
VOLUMES up to m3 22 8 2.5 12

 

  • 43 Reactors with a total reactor volume of 340 m³ (glass-lined, hastelloy, stainless steel) with a temperature range from -30°C to +250°C
  • 13 Solid/liquid separation units (centrifuges, pressure nutsches up to 6m2)
  • 12 Dryers (paddle and nutsch dryers with 2-9 m3, temperature up to 200°C)
  • 5 Distillation columns (+ short path distillation)
  • Wiped film evaporator
  • 2 Gas phase reactors including peripherals
  • Air jet mills

News

A special technology established at AlzChem is the use of Sodium borohydride for reductions in technical scale. The compound is an efficient and selective reducing agent for a series of organic molecules. AlzChem has appropriate equipment and suitable processes for a safe application and knows how to handle this challenging reagent.
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Company aims to markedly expand its global market position with investments of EUR 7.2 million and a significant increase in capacities Broadening the product range will open new target markets and applications Trostberg, September 6, 2018 - AlzChem Group AG has begun its significant expansion of its nitrile business. With an investment volume of EUR 7.2 million, AlzChem will increase production capacities for nitriles by mid-2019. The expansion of this product segment is part of a...
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A prime example of this are our Melflock® products, which are mostly used as flocculants in the paper and water treatment industries. Because of the backward integration of our most important raw material ‘Dicyandiamide’ we can ensure the availability of all our Melflock® products. The diligent work of our customer service and logistic department is the reason why we can keep up with regular delivery times within Europe, whereas the European transport market itself is running into trouble...
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Trostberg. Amidines are organic chemical compounds with an NCN structure, meaning a typical nitrogen-carbon-nitrogen sequence. These types of chemicals are one of AlzChem’s core competencies. NCN structures are contained in many biologically active molecules, which is why a general new synthesis method is so important to the development and production of active ingredients in pharmaceuticals and crop protection. Amidines to this point have been difficult to synthesize, particularly without...
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